Analyze data, write and execute R and Python, build publication-quality visualizations, and perform clinical research analysis, all in one intelligent workspace.
Each studio is purpose-built for a different aspect of statistical computing and clinical research, seamlessly connected through a unified interface.
From AI-powered code generation to GxP-validated clinical deliverables, every feature is engineered for rigor, speed, and compliance.
Intelligent coding assistant that understands R, Python, and clinical biostatistics. Ask questions in plain English and get production-grade code with explanations. Supports multi-turn conversations with full context awareness.
Native R process (R 4.6.1) and Python (3.12) execution side-by-side with full package ecosystems. Switch seamlessly between languages with shared data context and in-memory DuckDB for zero-latency clinical transformations.
Auto-generate Table 14.1.1 demographics, safety AE tables, lab shift matrices, and efficacy summaries with population filters (ITT, Safety, Per-Protocol). Export directly to Word/PDF for CSR appendices.
Drag-and-drop visual builder generating live ggplot2 and Seaborn/Matplotlib code. Create Kaplan-Meier curves, swimmer plots, forest plots, box plots, and more with interactive hover inspection.
Interactive patient-level tumor burden tracker with RECIST 1.1 milestones: complete response (CR), partial response (PR), stable disease (SD), and ongoing treatment markers.
Cryptographic SHA-256 database lock ceremony with legally binding electronic signatures, tamper-evident audit logs, non-repudiation PIN signing, and downloadable TMF certificates.
Automated double-programming comparison between R primary scripts and SAS/R QC code with configurable floating-point tolerances (1e-4 to 1e-8). Generates reconciliation certificates.
Interactive SAP designer with BOIN dose-escalation algorithms, ICH E9(R1) estimand framework, regulatory templates, AI drafting copilot, and full amendment tracking.
Full-featured Quarto/Rmd authoring environment with live preview, parameterized regulatory reports, and one-click rendering to HTML, PDF, Word, and PowerPoint for CSR dossiers.
Cell-by-cell interactive notebook supporting both R and Python in the same document. Execute, visualize, annotate, and share analyses with rich markdown cells and code outputs.
Kanban deliverables board, Gantt charts, budget tracking, delay monitoring, and study timeline management. Keep clinical programming teams aligned and on schedule.
First-class support for ADSL, ADAE, ADLB, ADTTE, and ADTRBC domains. Built-in CDISC variable dictionaries, derivation traceability, and Pinnacle 21 validation integration.
Access every tool you need for clinical programming, regulatory submission, and statistical analysis, all integrated directly into the studio.
Live R execution environment with path scanner and system diagnostics
R 4.6.1GxP reproducible dependency snapshots via Posit Package Manager
GxPValidated clinical biostatistics and TLF templates for R and Python
LibraryVisual annotation mapping clinical variables to CDASH and SDTM domains
SDTMUpload protocol or SAP to synthesize production-grade R/Python code
AI EngineCompile tables into unified CSR Section 14 appendices and eCTD modules
CSR 14.xAutomated FDA rejection rule compliance with auto-remediation suggestions
Pinnacle 21Blind double-programming reconciliation and statistical output diff engine
ValidationCron batch pipelines, scheduled execution and automated report delivery
AutomationLive dual-programmer pair coding and biostatistical study chat
LiveChronological code snapshots, revision timeline, and one-click rollback
AuditSAS7BDAT, SQL databases, EDC interfaces, and S3 cloud data lakes
Data LakeICH E9(R1) estimand extractor, power calculator, and statistical advisor
ICH E9(R1)Electronic signature and cryptographic study freeze for database lock
21 CFR 11Analysis Data Reviewer's Guide auto-compiler for eCTD Module 5.3.5.3
eCTDMulti-domain chronological event timeline (ICH E3 Fig 14.3.1)
ICH E3Submit feedback, report issues, and track responses from the engineering team
SupportAdmin-level control to show/hide any studio tabs, tools, or menus
AdminEvery tool meets strict pharmaceutical regulatory requirements out of the box, with no additional validation needed.
Full electronic records and signatures compliance with cryptographic integrity.
First-class support for all major CDISC data standards and dictionaries.
End-to-end support for ICH guidelines throughout the study lifecycle.
Every result is reproducible, auditable, and traceable from protocol to submission.
Experience the cryptographic database lock process. Enter your credentials to generate an immutable SHA-256 digital signature.
RPWisdom AI works as a cloud web application and as an installable desktop app via PWA. Zero installation required.
Access instantly at rpwisdom.com from any browser. Powered by Railway with auto-scaling, HTTPS, and global edge caching. No setup, no downloads.
Install as a native desktop app directly from your browser. Works offline, launches from taskbar, and receives automatic updates via service worker.
Deploy on-premises with the production Dockerfile. Includes R, Python, Node.js, and all clinical packages pre-installed. FDA-compliant containerized deployment.
